当前位置：首页>产品中心>单抗/多抗>Anti-Human NHERF-3/PDZK1 Polyclonal Antibody|抗人NHERF-3/PDZK1多克隆抗体(靶标：人Na+/H+交换调节因子3/PDZK1)
Anti-Human NHERF-3/PDZK1 Polyclonal Antibody|抗人NHERF-3/PDZK1多克隆抗体(靶标：人Na+/H+交换调节因子3/PDZK1)
- 货号：RB9THA122014
- 价格：面议
- 点击：301
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CAP70, CFTR-associated protein of 70 kDa, NHERF-3, NHERF3, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Na(+)/H(+) exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein |
| 免疫原 | E. coli - derived recombinant Human NHERF-3/PDZK1 (Met1-Ser341). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q5T2W1 |
| 背景信息 | Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3/PDZK1) is a ~57 kDa protein. A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. |
| 备注 | For research use only |
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