Anti-Human NHERF-3/PDZK1 Polyclonal Antibody|抗人NHERF-3/PDZK1多克隆抗体(靶标：人Na+/H+交换调节因子3/PDZK1)

Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3/PDZK1) is a ~57 kDa protein. A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity.