Anti-Human SMPDL3B Polyclonal Antibody|抗人SMPDL3B多克隆抗体(靶标：人鞘磷脂磷酸二酯酶酸样3B)
- 货号：RB9THD667014
- 价格：面议
- 点击：218
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | ASM-like phosphodiesterase 3b, ASML3B, ASMLPD, Acid sphingomyelinase-like phosphodiesterase 3b, EC:3.1.4.-, SMPDL3B |
| 免疫原 | E. coli - derived recombinant Human SMPDL3B (Gly21-Gly433). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q92485 |
| 背景信息 | Acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) is a ~50 kDa protein. Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro). 1. Heinz, LX. et al. (2015) Cell reports 11, 1919-28. PMID: 26095358 |
| 备注 | For research use only |
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