Anti-Human ERO1A Polyclonal Antibody|抗人ERO1A多克隆抗体(靶标：人内质网氧化还原酶1α)
- 货号：RB9THD671014
- 价格：面议
- 点击：364
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Human, Mouse |
| 靶标 | EC:1.8.3.2, ERO1-L, ERO1-L-alpha, ERO1-like protein alpha, ERO1A, ERO1L, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha |
| 免疫原 | E. coli - derived recombinant Human ERO1A (Glu51-His468). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q96HE7 |
| 背景信息 | ERO1-like protein alpha (ERO1A) is a ~54 kDa protein. Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1. 1. Zhang, J. et al. (2018) The EMBO journal 37. PMID: 29858230 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7494 |
| 人触珠蛋白单克隆抗体 | 7682 |
| 贾第鞭毛虫单克隆抗体 | 7351 |
| 阿米巴单克隆抗体 | 7859 |
| 胃蛋白酶单克隆抗体 | 7380 |
| 胃蛋白酶原II单克隆抗体 | 7566 |
| 胃蛋白酶原I单克隆抗体 | 7299 |
| 艰难梭菌毒素A单克隆抗体 | 7448 |
| 艰难梭菌毒素B单克隆抗体 | 7739 |
| 艰难梭菌GDH单克隆抗体 | 7745 |
| 诺如病毒单克隆抗体 | 7238 |
| 伤寒沙门氏菌单克隆抗体 | 7315 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6837 |
| 幽门螺杆菌单克隆抗体 | 7350 |
| 钙卫蛋白单克隆抗体 | 7134 |
| 乳铁蛋白单克隆抗体 | 7473 |
| 转铁蛋白单克隆抗体 | 7475 |
| 血红蛋白单克隆抗体 | 7207 |
| 腺病毒单克隆抗体 | 7424 |
| 轮状病毒单克隆抗体 | 7800 |