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Anti-Human ALX1 Polyclonal Antibody|抗人ALX1多克隆抗体(靶标:人ALX同源盒蛋白1)

  • 货号:RB9THD673014
  • 价格:面议
  • 点击:227

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse, Rat
靶标ALX homeobox protein 1, ALX1, CART-1, CART1, Cartilage homeoprotein 1
免疫原E. coli - derived recombinant Human ALX1 (Arg136-Met326).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q15699
背景信息

ALX homeobox protein 1 (ALX1) is a ~36 kDa protein. Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1.

1. Gordon, DF. et al. (1996) DNA and cell biology 15, 531-41. PMID: 8756334
2. Cai, RL. (1998) Biochemical and biophysical research communications 250, 305-11. PMID: 9753625
3. Uz, E. et al. (2010) American journal of human genetics 86, 789-96. PMID: 20451171
4. Yuan, H. et al. (2013) Cancer research 73, 1581-90. PMID: 23288509
备注For research use only
【仅供科学研究使用】

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