当前位置:首页>产品中心>单抗/多抗>Anti-Human RNLS/Renalase Polyclonal Antibody|抗人RNLS/Renalase多克隆抗体(靶标:人肾酶/Renalase)

Anti-Human RNLS/Renalase Polyclonal Antibody|抗人RNLS/Renalase多克隆抗体(靶标:人肾酶/Renalase)

  • 货号:RB9THV286014
  • 价格:面议
  • 点击:590
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标C10orf59, EC:1.6.3.5, MAO-C, Monoamine oxidase-C, RNLS, Renalase
免疫原E. coli - derived recombinant Human RNLS/Renalase (Ala2-Ile342).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q5VYX0
背景信息

Renalase (RNLS) is a ~37 kDa protein. Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

备注For research use only
【仅供科学研究使用】

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