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Anti-Human RNLS/Renalase Polyclonal Antibody|抗人RNLS/Renalase多克隆抗体(靶标：人肾酶/Renalase)
- 货号：RB9THV286014
- 价格：面议
- 点击：521
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | C10orf59, EC:1.6.3.5, MAO-C, Monoamine oxidase-C, RNLS, Renalase |
| 免疫原 | E. coli - derived recombinant Human RNLS/Renalase (Ala2-Ile342). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q5VYX0 |
| 背景信息 | Renalase (RNLS) is a ~37 kDa protein. Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. |
| 备注 | For research use only |
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