Anti-Human MIEF1 Polyclonal Antibody|抗人MIEF1多克隆抗体(靶标：人线粒体延伸因子1)
- 货号：RB9THD501014
- 价格：面议
- 点击：265
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | AltMIEF1, AltMiD51, Alternative MIEF1 protein, MIEF1, MIEF1 microprotein, MIEF1-MP, Mitochondrial ribosome and complex I assembly factor AltMIEF1, alternative transcript upstream of MiD51 |
| 免疫原 | E. coli - derived recombinant Human MIEF1 (Ala2-Ile70). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | L0R8F8 |
| 背景信息 | Mitochondrial ribosome and complex I assembly factor AltMIEF1 is a ~8 kDa protein. Assembly factor involved in the biogenesis of the mitochondrial-specific ribosomes (mitoribosomes). Specifically associates with intermediates of the mitochondrial ribosome large subunit (mt-LSU) and is required for proper ribosome assembly, possibly preventing premature association of the large and small ribosomal subunits. Thereby, indirectly regulates mitochondrial translation. It is also required for complete assembly of the mitochondrial respiratory chain complex I. May also function in DNM1L-mediated mitochondrial fission. 1. Brown, A. et al. (2017) Nature structural & molecular biology 24, 866-869. PMID: 28892042 2. Rathore, A. et al. (2018) Biochemistry 57, 5564-5575. PMID: 30215512 3. Dibley, MG. et al. (2020) Molecular & cellular proteomics : MCP 19, 65-77. PMID: 31666358 |
| 备注 | For research use only |
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