| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Human, Mouse |
| 靶标 | ADP-ribosylation factor-like protein 1, ARL1 |
| 免疫原 | E. coli - derived recombinant Human ARL1 (Met1-Gln181). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P40616 |
| 背景信息 | ADP-ribosylation factor-like protein 1 (ARL1) is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. 1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483 2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020 3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159 4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755 5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189 6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563 7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988 |
| 备注 | For research use only |