当前位置:首页>产品中心>单抗/多抗>Anti-Human ARL1 Polyclonal Antibody|抗人ARL1多克隆抗体(靶标:人ADP核糖基化因子样蛋白1)

Anti-Human ARL1 Polyclonal Antibody|抗人ARL1多克隆抗体(靶标:人ADP核糖基化因子样蛋白1)

  • 货号:RB9THD512014
  • 价格:面议
  • 点击:395
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Human, Mouse
靶标ADP-ribosylation factor-like protein 1, ARL1
免疫原E. coli - derived recombinant Human ARL1 (Met1-Gln181).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P40616
背景信息

ADP-ribosylation factor-like protein 1 (ARL1) is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells.

1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483
2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020
3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159
4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755
5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189
6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563
7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988
备注For research use only
【仅供科学研究使用】

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