Anti-Human CD104/ITGB4 Polyclonal Antibody|抗人CD104/ITGB4多克隆抗体(靶标：人整合素β4亚基/CD104)
- 货号：RB9THB684014
- 价格：面议
- 点击：505
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CD104, GP150, ITGB4, Integrin beta-4 |
| 免疫原 | E. coli - derived recombinant Human CD104/ITGB4 (Leu923-Cys1197). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P16144 |
| 背景信息 | Integrin beta-4 (CD104/ITGB4) is a ~202 kDa protein. Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760 3. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7368 |
| 人触珠蛋白单克隆抗体 | 7581 |
| 贾第鞭毛虫单克隆抗体 | 7253 |
| 阿米巴单克隆抗体 | 7736 |
| 胃蛋白酶单克隆抗体 | 7271 |
| 胃蛋白酶原II单克隆抗体 | 7396 |
| 胃蛋白酶原I单克隆抗体 | 7192 |
| 艰难梭菌毒素A单克隆抗体 | 7306 |
| 艰难梭菌毒素B单克隆抗体 | 7601 |
| 艰难梭菌GDH单克隆抗体 | 7559 |
| 诺如病毒单克隆抗体 | 7111 |
| 伤寒沙门氏菌单克隆抗体 | 7230 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6738 |
| 幽门螺杆菌单克隆抗体 | 7237 |
| 钙卫蛋白单克隆抗体 | 7073 |
| 乳铁蛋白单克隆抗体 | 7364 |
| 转铁蛋白单克隆抗体 | 7357 |
| 血红蛋白单克隆抗体 | 7123 |
| 腺病毒单克隆抗体 | 7312 |
| 轮状病毒单克隆抗体 | 7645 |