Anti-Human NOTCH3 Polyclonal Antibody|抗人NOTCH3多克隆抗体(靶标：人Notch同源物3)
- 货号：RB9THV701014
- 价格：面议
- 点击：529
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | NOTCH3, Neurogenic locus notch homolog protein 3, Notch 3, Notch 3 extracellular truncation, Notch 3 intracellular domain |
| 免疫原 | E. coli - derived recombinant Human NOTCH3 (Ala40-Glu467). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UM47 |
| 背景信息 | Neurogenic locus notch homolog protein 3 (NOTCH3) is a ~243 kDa protein. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD), it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. 1. Peters, N. et al. (2004) Experimental cell research 299, 454-64. PMID: 15350543 2. Joutel, A. et al. (2004) American journal of human genetics 74, 338-47. PMID: 14714274 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 过氧化物酶（HRP）标莱克多巴胺单克隆抗体 | 5868 |
| 过氧化物酶（HRP）标沙丁胺醇单克隆抗体 | 5814 |
| 呋喃唑酮代谢物（2-NPAOZ）单抗 | 6301 |
| 环丙沙星（CPFX）单抗 | 5732 |
| 氟喹诺酮类单抗 | 5844 |
| 恩诺沙星单抗 | 5738 |
| 环丙沙星|恩诺沙星|诺氟沙星三合一单抗 | 5810 |
| 睾酮单抗 | 5722 |
| 过氧化物酶（HRP）标睾酮单克隆抗体 | 5635 |
| 过氧化物酶（HRP）标雌三醇单克隆抗体 | 5878 |
| 过氧化物酶（HRP）标记甲基睾酮单克隆抗体 | 6071 |
| 黄曲霉毒素抗体（黄曲霉毒素B1，黄曲霉毒素总量单克隆抗体） | 5696 |
| 苏丹红1号单抗 | 5990 |
| 呋喃西林代谢物（2-NPSEM）单抗（40F11细胞株） | 5577 |
| 小鼠单克隆抗体Ig类/亚类鉴定ELISA试剂盒 | 6509 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定ELISA试剂盒 | 6744 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定酶标二抗即用套装 | 6672 |
| HRP标记小鼠单抗专用稀释液 | 6722 |
| 小鼠单抗腹水制备专用佐剂套装 | 6746 |
| 新冠病毒S蛋白中和抗体ELISA检测试剂盒 | 6521 |