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Anti-Human TBL1X Polyclonal Antibody|抗人TBL1X多克隆抗体(靶标:人转导蛋白样β1X连锁)

  • 货号:RB9THF868014
  • 价格:面议
  • 点击:265

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human
靶标F-box-like/WD repeat-containing protein TBL1X, SMAP55, TBL1, TBL1X, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked
免疫原E. coli - derived recombinant Human TBL1X (Val218-Lys577).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O60907
背景信息

F-box-like/WD repeat-containing protein TBL1X is a ~62 kDa protein. F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

1. Perissi, V. et al. (2004) Cell 116, 511-26. PMID: 14980219
2. Oberoi, J. et al. (2011) Nature structural & molecular biology 18, 177-84. PMID: 21240272
备注For research use only
【仅供科学研究使用】

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