Anti-Human GAR1 Polyclonal Antibody|抗人GAR1多克隆抗体(靶标：人GAR1核仁蛋白)
- 货号：RB9THD530014
- 价格：面议
- 点击：190
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | GAR1, H/ACA ribonucleoprotein complex subunit 1, NOLA1, Nucleolar protein family A member 1, snoRNP protein GAR1 |
| 免疫原 | E. coli - derived recombinant Human GAR1 (Val71-Arg160). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9NY12 |
| 背景信息 | H/ACA ribonucleoprotein complex subunit 1 (GAR1) is a ~22 kDa protein. Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. |
| 备注 | For research use only |
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