当前位置：首页>产品中心>单抗/多抗>Anti-Human CD242/ICAM4 Polyclonal Antibody|抗人CD242/ICAM4多克隆抗体(靶标：人细胞间黏附分子4/CD242)
Anti-Human CD242/ICAM4 Polyclonal Antibody|抗人CD242/ICAM4多克隆抗体(靶标：人细胞间黏附分子4/CD242)
- 货号：RB9THC421014
- 价格：面议
- 点击：358
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CD242, ICAM-4, ICAM4, Intercellular adhesion molecule 4, LW, LW blood group protein, Landsteiner-Wiener blood group glycoprotein |
| 免疫原 | E. coli - derived recombinant Human CD242/ICAM4 (Met52-Trp234). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q14773 |
| 背景信息 | Intercellular adhesion molecule 4 (CD242/ICAM4) is a ~29 kDa protein. Functions as a receptor ligand for the monocyte/macrophage-specific ITGAX:ITGB2 integrin complex and mediates erythrophagocytosis. Receptor ligand of the platelet-specific ITGA2B:ITGB3 integrin complex involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets. In vitro, is also a receptor ligand of multiple integrin receptors complexes such ITGAL:ITGB2, ITGAM:ITGB2, ITGA5:ITGB1, ITGA5:ITGB3 and ITGA5:ITGB5 integrin complexes. 1. Ihanus, E. et al. (2007) Blood 109, 802-10. PMID: 16985175 2. Hermand, P. et al. (2003) The Journal of biological chemistry 278, 4892-8. PMID: 12477717 3. Hermand, P. et al. (2004) European journal of biochemistry 271, 3729-40. PMID: 15355350 4. Hermand, P. et al. (2000) The Journal of biological chemistry 275, 26002-10. PMID: 10846180 5. Spring, FA. et al. (2001) Blood 98, 458-66. PMID: 11435317 |
| 备注 | For research use only |
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