| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | Epididymis tissue protein Li 185a, NMB-R, NMBR, Neuromedin-B receptor, Neuromedin-B-preferring bombesin receptor |
| 免疫原 | E. coli - derived recombinant Human NMBR (Pro2-Val41&Asp100-Lys117&Glu178-Ile211&Ser328-Leu390). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P28336 |
| 背景信息 | Neuromedin-B receptor (NMBR) is a ~43 kDa protein. Receptor for neuromedin-B. Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem. These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response. Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide. 1. Corjay, MH. et al. (1991) The Journal of biological chemistry 266, 18771-9. PMID: 1655761 2. Yang, G. et al. (2019) Veterinary research 50, 80. PMID: 31601264 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 7083 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6571 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6991 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6901 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6655 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6505 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6770 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6503 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6344 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(6种) | 6497 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(6种) | 6474 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒(6种) | 6632 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(8种) | 6377 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(8种) | 6600 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒(8种) | 6680 |
| 单抗融合无忧套装 | 6781 |
| 即用型单抗细胞融合/亚克培养基 | 6462 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6785 |
| 通用型抗体稀释液 | 6394 |
| HRP酶标抗体稀释液 | 6591 |