| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | Epididymis tissue protein Li 185a, NMB-R, NMBR, Neuromedin-B receptor, Neuromedin-B-preferring bombesin receptor |
| 免疫原 | E. coli - derived recombinant Human NMBR (Pro2-Val41&Asp100-Lys117&Glu178-Ile211&Ser328-Leu390). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P28336 |
| 背景信息 | Neuromedin-B receptor (NMBR) is a ~43 kDa protein. Receptor for neuromedin-B. Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem. These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response. Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide. 1. Corjay, MH. et al. (1991) The Journal of biological chemistry 266, 18771-9. PMID: 1655761 2. Yang, G. et al. (2019) Veterinary research 50, 80. PMID: 31601264 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6256 |
| 多菌灵/阿苯达唑二合一单抗 | 6308 |
| 三氯噻嗪单抗 | 6410 |
| 吡唑醚菌酯单抗 | 6611 |
| 烯酰吗啉单抗 | 6417 |
| 抑霉唑单抗 | 6159 |
| 恶醚唑(苯醚甲环唑)单抗 | 6335 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6362 |
| 辛硫磷单抗 | 6419 |
| 多效唑单抗 | 6264 |
| 对硫磷单抗 | 6502 |
| 丙溴磷单抗 | 6519 |
| 戊唑醇单抗 | 6504 |
| 莠去津单抗 | 6418 |
| 灭蝇胺单抗 | 6106 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6402 |
| 2.4-二氯苯氧乙酸单抗 | 6246 |
| 甲基对硫磷单抗 | 6331 |
| 左旋咪唑单抗 | 6258 |
| 三唑磷单抗 | 6323 |