当前位置:首页>产品中心>单抗/多抗>Anti-Human CASQ2 Polyclonal Antibody|抗人CASQ2多克隆抗体(靶标:人肌钙腔蛋白2/Calsequestrin-2)

Anti-Human CASQ2 Polyclonal Antibody|抗人CASQ2多克隆抗体(靶标:人肌钙腔蛋白2/Calsequestrin-2)

  • 货号:RB9THD535014
  • 价格:面议
  • 点击:233

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标CASQ2, Calsequestrin, cardiac muscle isoform, Calsequestrin-2
免疫原E. coli - derived recombinant Human CASQ2 (Lys40-Gly368).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O14958
背景信息

Calsequestrin-2 (CASQ2) is a ~46 kDa protein. Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.

备注For research use only
【仅供科学研究使用】

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