当前位置:首页>产品中心>单抗/多抗>Anti-Human HDAC7 Polyclonal Antibody|抗人HDAC7多克隆抗体(靶标:人组蛋白去乙酰化酶7)

Anti-Human HDAC7 Polyclonal Antibody|抗人HDAC7多克隆抗体(靶标:人组蛋白去乙酰化酶7)

  • 货号:RB9THV082014
  • 价格:面议
  • 点击:423

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human
靶标EC:3.5.1.-, EC:3.5.1.98, HD7, HD7a, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, Protein deacetylase HDAC7
免疫原E. coli - derived recombinant Human HDAC7 (Ser482-Ser903).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q8WUI4
背景信息

Histone deacetylase 7 (HDAC7) is a ~102 kDa protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

1. Bryant, H. et al. (2002) Journal of virology 76, 10290-8. PMID: 12239305
2. Li, B. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 4571-6. PMID: 17360565
3. Lee, DY. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 2072-2077. PMID: 28167758
4. Zhang, XL. et al. (2023) Nature communications 14, 3815. PMID: 37369679
备注For research use only
【仅供科学研究使用】

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