| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | EC:3.5.1.-, EC:3.5.1.98, HD7, HD7a, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, Protein deacetylase HDAC7 |
| 免疫原 | E. coli - derived recombinant Human HDAC7 (Ser482-Ser903). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8WUI4 |
| 背景信息 | Histone deacetylase 7 (HDAC7) is a ~102 kDa protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. 1. Bryant, H. et al. (2002) Journal of virology 76, 10290-8. PMID: 12239305 2. Li, B. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 4571-6. PMID: 17360565 3. Lee, DY. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 2072-2077. PMID: 28167758 4. Zhang, XL. et al. (2023) Nature communications 14, 3815. PMID: 37369679 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 7687 |
| 白细胞介素6(IL-6)单克隆抗体 | 7385 |
| 肝素结合蛋白单克隆抗体 | 6858 |
| CRP单克隆抗体 | 7696 |
| 猫胰脂肪酶单克隆抗体 | 7204 |
| 马SAA单克隆抗体 | 7592 |
| 犬腺病毒单克隆抗体 | 6926 |
| 犬轮状病毒单克隆抗体 | 7012 |
| 犬血红蛋白单克隆抗体 | 7983 |
| 犬胰脂肪酶单克隆抗体 | 6817 |
| 犬松弛素单克隆抗体 | 7184 |
| 犬冠状病毒单克隆抗体 | 7197 |
| 犬瘟病毒单克隆抗体 | 6912 |
| 犬细小病毒单克隆抗体 | 7360 |
| 猫瘟病毒单克隆抗体 | 7493 |
| 猫疱疹病毒单克隆抗体 | 7235 |
| 猫杯状病毒单克隆抗体 | 7657 |
| 猫SAA单克隆抗体 | 7299 |
| 犬CRP单克隆抗体 | 7827 |
| 犬、猫IgG单克隆抗体 | 7176 |