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Anti-Human KL Polyclonal Antibody|抗人KL多克隆抗体(靶标:人Klotho蛋白)

  • 货号:RB9THV160014
  • 价格:面议
  • 点击:203

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标EC:3.2.1.31, KL, Klotho, Klotho peptide
免疫原E. coli - derived recombinant Human KL (Glu34-Ser981).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9UEF7
背景信息

Klotho is a ~116 kDa protein. May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.

备注For research use only
【仅供科学研究使用】

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