Anti-Human YJEFN3 Polyclonal Antibody|抗人YJEFN3多克隆抗体(靶标：人YjeF N端结构域含蛋白3)
- 货号：RB9THT044014
- 价格：面议
- 点击：546
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | AIBP2, ApoA-I-binding protein 2, YJEFN3, YjeF N-terminal domain-containing protein 3, YjeF_N3, hYjeF_N3 |
| 免疫原 | E. coli - derived recombinant Human YJEFN3 (Met1-Leu299). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | A6XGL0 |
| 背景信息 | YjeF N-terminal domain-containing protein 3 (YJEFN3) is a ~32 kDa protein. May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis. 1. Rudolph, C. et al. (2007) Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 39, 322-35. PMID: 17533573 |
| 备注 | For research use only |
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