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Anti-Human MBP Polyclonal Antibody|抗人MBP多克隆抗体(靶标:人髓鞘碱性蛋白)
- 货号:RB9THF789014
- 价格:面议
- 点击:291
产品介绍
产品参数
| 形态 | Liquid |
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| 宿主种属 | Rabbit |
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| 克隆性 | Polyclonal |
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| 抗体亚型 | IgG |
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| 纯化方式 | Purified by antigen affinity column. |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, IHC, WB |
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| 种属反应性 | Human, Rat |
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| 靶标 | MBP, Myelin A1 protein, Myelin basic protein, Myelin membrane encephalitogenic protein |
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| 免疫原 | E. coli - derived recombinant Human MBP (Met1-Lys192). |
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| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
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| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
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| 登录号 | P02686 |
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| 背景信息 | Myelin basic protein (MBP) is a ~33 kDa protein. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. |
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| 备注 | For research use only |
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【仅供科学研究使用】
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