| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | ER protein 44, ERP44, ERp44, Endoplasmic reticulum resident protein 44, KIAA0573, TXNDC4, Thioredoxin domain-containing protein 4 |
| 免疫原 | E. coli - derived recombinant Human ERP44 (Thr36-Leu406). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9BS26 |
| 背景信息 | Endoplasmic reticulum resident protein 44 (ERP44) is a ~46 kDa protein. Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. 1. Anelli, T. et al. (2002) The EMBO journal 21, 835-44. PMID: 11847130 2. Anelli, T. et al. (2003) The EMBO journal 22, 5015-22. PMID: 14517240 3. Higo, T. et al. (2005) Cell 120, 85-98. PMID: 15652484 4. Zhang, J. et al. (2018) The EMBO journal 37. PMID: 29858230 |
| 备注 | For research use only |