当前位置:首页>产品中心>单抗/多抗>Anti-Human ERP44 Polyclonal Antibody|抗人ERP44多克隆抗体(靶标:人内质网蛋白44)

Anti-Human ERP44 Polyclonal Antibody|抗人ERP44多克隆抗体(靶标:人内质网蛋白44)

  • 货号:RB9THD557014
  • 价格:面议
  • 点击:345

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human
靶标ER protein 44, ERP44, ERp44, Endoplasmic reticulum resident protein 44, KIAA0573, TXNDC4, Thioredoxin domain-containing protein 4
免疫原E. coli - derived recombinant Human ERP44 (Thr36-Leu406).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9BS26
背景信息

Endoplasmic reticulum resident protein 44 (ERP44) is a ~46 kDa protein. Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.

1. Anelli, T. et al. (2002) The EMBO journal 21, 835-44. PMID: 11847130
2. Anelli, T. et al. (2003) The EMBO journal 22, 5015-22. PMID: 14517240
3. Higo, T. et al. (2005) Cell 120, 85-98. PMID: 15652484
4. Zhang, J. et al. (2018) The EMBO journal 37. PMID: 29858230
备注For research use only
【仅供科学研究使用】

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