Anti-Human FMO1 Polyclonal Antibody|抗人FMO1多克隆抗体(靶标：人含黄素单加氧酶1)
- 货号：RB9THD564014
- 价格：面议
- 点击：344
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, EC:1.14.13.148, EC:1.14.13.8, FMO 1, FMO1, Fetal hepatic flavin-containing monooxygenase 1, Flavin-containing monooxygenas |
| 免疫原 | E. coli - derived recombinant Human FMO1 (Met1-Pro510). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q01740 |
| 背景信息 | Flavin-containing monooxygenase 1 (FMO1) is a ~60 kDa protein. Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. 1. Veeravalli, S. et al. (2020) Drug metabolism and disposition: the biological fate of chemicals 48, 378-385. PMID: 32156684 |
| 备注 | For research use only |
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