| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | EC:2.7.1.137, EC:2.7.1.153, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PIK3CD, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, Phosphatidylinositol 4,5-bisphospha |
| 免疫原 | E. coli - derived recombinant Human PIK3CD (Val774-Gln1044). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O00329 |
| 背景信息 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) is a ~119 kDa protein. Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides. Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. 1. Chantry, D. et al. (1997) The Journal of biological chemistry 272, 19236-41. PMID: 9235916 2. Meier, TI. et al. (2004) Protein expression and purification 35, 218-24. PMID: 15135396 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5697 |
| 金刚烷胺单抗 | 5737 |
| 卡那霉素单抗 | 5871 |
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| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 6224 |
| 帕托珠利(妥曲珠利砜)单抗 | 5723 |
| 泰乐菌素单抗 | 5850 |
| 替米考星单抗 | 5877 |
| 新霉素单抗 | 5889 |
| 安普霉素单抗 | 5865 |
| 三聚氰胺(MEL)单抗 | 5763 |
| 双氟沙星单抗 | 5728 |
| 西地那非单抗 | 5808 |
| 阿苯达唑单抗 | 5616 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5782 |
| 氟苯尼考单抗 | 5828 |
| 诺龙单抗 | 5908 |
| 达氟沙星单抗 | 6014 |
| 培氟沙星单抗 | 5862 |
| 庆大霉素单抗 | 5989 |