| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | EC:2.7.1.137, EC:2.7.1.153, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PIK3CD, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, Phosphatidylinositol 4,5-bisphospha |
| 免疫原 | E. coli - derived recombinant Human PIK3CD (Val774-Gln1044). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O00329 |
| 背景信息 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) is a ~119 kDa protein. Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides. Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Mediates immune responses. Plays a role in B-cell development, proliferation, migration, and function. 1. Chantry, D. et al. (1997) The Journal of biological chemistry 272, 19236-41. PMID: 9235916 2. Meier, TI. et al. (2004) Protein expression and purification 35, 218-24. PMID: 15135396 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6339 |
| 多菌灵/阿苯达唑二合一单抗 | 6414 |
| 三氯噻嗪单抗 | 6512 |
| 吡唑醚菌酯单抗 | 6749 |
| 烯酰吗啉单抗 | 6585 |
| 抑霉唑单抗 | 6275 |
| 恶醚唑(苯醚甲环唑)单抗 | 6443 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6471 |
| 辛硫磷单抗 | 6538 |
| 多效唑单抗 | 6428 |
| 对硫磷单抗 | 6622 |
| 丙溴磷单抗 | 6678 |
| 戊唑醇单抗 | 6673 |
| 莠去津单抗 | 6536 |
| 灭蝇胺单抗 | 6211 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6490 |
| 2.4-二氯苯氧乙酸单抗 | 6339 |
| 甲基对硫磷单抗 | 6413 |
| 左旋咪唑单抗 | 6360 |
| 三唑磷单抗 | 6439 |