| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | EC:3.4.-.-, LACTB, MRPL56, Serine beta-lactamase-like protein LACTB, mitochondrial |
| 免疫原 | E. coli - derived recombinant Human LACTB (Cys100-Ser256). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P83111 |
| 背景信息 | Serine beta-lactamase-like protein LACTB, mitochondrial is a ~60 kDa protein. Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism. 1. Keckesova, Z. et al. (2017) Nature 543, 681-686. PMID: 28329758 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5990 |
| 西马特罗单抗 | 6018 |
| 孕酮单抗 | 6152 |
| 氯霉素(CAP)单抗 | 6106 |
| 红霉素单抗 | 6097 |
| 地克珠利单抗 | 5795 |
| 无色孔雀石绿(LMG)单抗 | 6034 |
| 雌二醇单抗 | 5763 |
| 孔雀石绿(MG)单抗 | 6188 |
| 双酚A单抗 | 6033 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5850 |
| 己烯雌酚单抗 | 5932 |
| 莱克多巴胺(RAC)单抗 | 6111 |
| 林可霉素单抗 | 6465 |
| 抗青霉素受体单抗 | 5818 |
| 大观霉素单抗 | 5919 |
| 克伦特罗(CL)单抗 | 6142 |
| 沙拉沙星单抗(2H4) | 5970 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 6109 |
| 磺胺类SAS单抗 | 6020 |