当前位置:首页>产品中心>单抗/多抗>Anti-Human PRC1 Polyclonal Antibody|抗人PRC1多克隆抗体(靶标:人胞质分裂调节蛋白1)

Anti-Human PRC1 Polyclonal Antibody|抗人PRC1多克隆抗体(靶标:人胞质分裂调节蛋白1)

  • 货号:RB9THD582014
  • 价格:面议
  • 点击:205
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标PRC1, Protein regulator of cytokinesis 1
免疫原E. coli - derived recombinant Human PRC1 (Met1-Ser466).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O43663
背景信息

Protein regulator of cytokinesis 1 (PRC1) is a ~71 kDa protein. Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.

1. Kanehira, M. et al. (2007) Cancer research 67, 3276-85. PMID: 17409436
备注For research use only
【仅供科学研究使用】

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