| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | A-kinase anchor protein 18 kDa, A-kinase anchor protein 7 isoforms alpha and beta, AKAP 18, AKAP-7 isoforms alpha and beta, AKAP15, AKAP18, AKAP7, PRKA7 isoforms alpha/beta, Protein kinase A-anchoring |
| 免疫原 | E. coli - derived recombinant Human AKAP7 (Met1-Lys104). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O43687 |
| 背景信息 | A-kinase anchor protein 7 isoforms alpha and beta (AKAP7) is a ~11 kDa protein. Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| 备注 | For research use only |