| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | ABP-280-like protein, ABP-L, ABPL, Actin-binding-like protein, FLN-C, FLN2, FLNC, FLNc, Filamin-2, Filamin-C, Gamma-filamin |
| 免疫原 | E. coli - derived recombinant Human FLNC (Glu17-Lys259). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q14315 |
| 背景信息 | Filamin-C (FLNC) is a ~291 kDa protein. Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events. 1. Agarwal, R. et al. (2021) Circulation research 129, 751-766. PMID: 34405687 |
| 备注 | For research use only |