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Anti-Human MOGAT2 Polyclonal Antibody|抗人MOGAT2多克隆抗体(靶标:人单酰甘油O-酰基转移酶2)

  • 货号:RB9THD596014
  • 价格:面议
  • 点击:379

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标2-acylglycerol O-acyltransferase 2, Acyl-CoA:monoacylglycerol acyltransferase 2, DC5, DGAT2L5, Diacylglycerol O-acyltransferase candidate 5, Diacylglycerol acyltransferase 2-like protein 5, EC:2.3.1.2
免疫原E. coli - derived recombinant Human MOGAT2 (His70-Cys334).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q3SYC2
背景信息

2-acylglycerol O-acyltransferase 2 (MOGAT2) is a ~38 kDa protein. Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0 at sn-2. Able to use 1-monoalkylglycerol (1-MAkG, 1-O-alkylglycerol) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG, 1-O-alkyl-3-acylglycerol or 1-O-alkyl-2-acylglycerol) and subsequently, with lower efficiency, may add another acyl chain producing monoalkyl-diacylglycerol (MADAG, 1-O-alkyl-2,3-diacylglycerol).

1. Yen, CL. et al. (2003) The Journal of biological chemistry 278, 18532-7. PMID: 12621063
2. Cheng, D. et al. (2008) The Journal of biological chemistry 283, 29802-11. PMID: 18768481
3. Brandt, C. et al. (2016) Biochemical and biophysical research communications 475, 264-70. PMID: 27184406
4. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705
备注For research use only
【仅供科学研究使用】

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