Anti-Human DKC1 Polyclonal Antibody|抗人DKC1多克隆抗体(靶标：人Dyskerin蛋白)
- 货号：RB9THD599014
- 价格：面议
- 点击：212
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | CBF5 homolog, DKC1, Dyskerin, EC:5.4.99.-, H/ACA ribonucleoprotein complex subunit DKC1, NOLA4, Nopp140-associated protein of 57 kDa, Nucleolar protein NAP57, Nucleolar protein family A member 4, snoR |
| 免疫原 | E. coli - derived recombinant Human DKC1 (Glu82-Ser295). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O60832 |
| 背景信息 | H/ACA ribonucleoprotein complex subunit DKC1 is a ~57 kDa protein. Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. 1. Schwartz, S. et al. (2014) Cell 159, 148-162. PMID: 25219674 2. Balogh, E. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 15137-15147. PMID: 32554502 3. Venteicher, AS. et al. (2009) Science (New York, N.Y.) 323, 644-8. PMID: 19179534 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6438 |
| 多菌灵/阿苯达唑二合一单抗 | 6568 |
| 三氯噻嗪单抗 | 6627 |
| 吡唑醚菌酯单抗 | 6982 |
| 烯酰吗啉单抗 | 6828 |
| 抑霉唑单抗 | 6444 |
| 恶醚唑（苯醚甲环唑）单抗 | 6610 |
| 赛拉嗪（甲苯噻嗪）单抗 | 6558 |
| 辛硫磷单抗 | 6671 |
| 多效唑单抗 | 6616 |
| 对硫磷单抗 | 6866 |
| 丙溴磷单抗 | 6839 |
| 戊唑醇单抗 | 6837 |
| 莠去津单抗 | 6698 |
| 灭蝇胺单抗 | 6408 |
| 尼卡巴嗪代谢物（DNC）单抗 | 6657 |
| 2.4-二氯苯氧乙酸单抗 | 6477 |
| 甲基对硫磷单抗 | 6549 |
| 左旋咪唑单抗 | 6544 |
| 三唑磷单抗 | 6605 |
