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Anti-Human AHI1 Polyclonal Antibody|抗人AHI1多克隆抗体(靶标:人Abelson辅助整合位点1)

  • 货号:RB9THV430014
  • 价格:面议
  • 点击:332

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标AHI-1, AHI1, Abelson helper integration site 1 protein homolog, Jouberin
免疫原E. coli - derived recombinant Human AHI1 (Arg596-Ile917).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q8N157
背景信息

Jouberin (AHI1) is a ~137 kDa protein. Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development.

1. Lancaster, MA. et al. (2011) Nature medicine 17, 726-31. PMID: 21623382
备注For research use only
【仅供科学研究使用】

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