| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | C17orf85, NCBP3, Nuclear cap-binding protein subunit 3, Protein ELG |
| 免疫原 | E. coli - derived recombinant Human NCBP3 (Asp79-Ile294). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q53F19 |
| 背景信息 | Nuclear cap-binding protein subunit 3 (NCBP3) is a ~70 kDa protein. Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth. 1. Gebhardt, A. et al. (2015) Nature communications 6, 8192. PMID: 26382858 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 7787 |
| 白细胞介素6(IL-6)单克隆抗体 | 7483 |
| 肝素结合蛋白单克隆抗体 | 6970 |
| CRP单克隆抗体 | 7868 |
| 猫胰脂肪酶单克隆抗体 | 7286 |
| 马SAA单克隆抗体 | 7792 |
| 犬腺病毒单克隆抗体 | 6998 |
| 犬轮状病毒单克隆抗体 | 7115 |
| 犬血红蛋白单克隆抗体 | 8138 |
| 犬胰脂肪酶单克隆抗体 | 6901 |
| 犬松弛素单克隆抗体 | 7305 |
| 犬冠状病毒单克隆抗体 | 7289 |
| 犬瘟病毒单克隆抗体 | 7022 |
| 犬细小病毒单克隆抗体 | 7506 |
| 猫瘟病毒单克隆抗体 | 7625 |
| 猫疱疹病毒单克隆抗体 | 7350 |
| 猫杯状病毒单克隆抗体 | 7785 |
| 猫SAA单克隆抗体 | 7372 |
| 犬CRP单克隆抗体 | 7910 |
| 犬、猫IgG单克隆抗体 | 7258 |