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Anti-Human SOX11 Polyclonal Antibody|抗人SOX11多克隆抗体(靶标:人SRY相关HMG盒转录因子11)

  • 货号:RB9THD615014
  • 价格:面议
  • 点击:235

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标SOX11, Transcription factor SOX-11
免疫原E. coli - derived recombinant Human SOX11 (Asn54-Tyr113).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P35716
背景信息

Transcription factor SOX-11 (SOX11) is a ~46 kDa protein. Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis.

1. Tsurusaki, Y. et al. (2014) Nature communications 5, 4011. PMID: 24886874
2. Hempel, A. et al. (2016) Journal of medical genetics 53, 152-62. PMID: 26543203
备注For research use only
【仅供科学研究使用】

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