| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | CCDC85B, Coiled-coil domain-containing protein 85B, DIPA, Delta-interacting protein A, Hepatitis delta antigen-interacting protein A |
| 免疫原 | E. coli - derived recombinant Human CCDC85B (Met1-Asp202). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q15834 |
| 背景信息 | Coiled-coil domain-containing protein 85B (CCDC85B) is a ~22 kDa protein. Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion. Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family. 1. Du, X. et al. (2006) Experimental and molecular pathology 81, 184-90. PMID: 17014843 2. Iwai, A. et al. (2008) Oncogene 27, 1520-6. PMID: 17873903 |
| 备注 | For research use only |