Anti-Human KLF10 Polyclonal Antibody|抗人KLF10多克隆抗体(靶标：人Krüppel样转录因子10)
- 货号：RB9THC085014
- 价格：面议
- 点击：617
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | EGR-alpha, KLF10, Krueppel-like factor 10, TGFB-inducible early growth response protein 1, TIEG, TIEG-1, TIEG1, Transforming growth factor-beta-inducible early growth response protein 1 |
| 免疫原 | E. coli - derived recombinant Human KLF10 (Lys382-Gln480). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13118 |
| 背景信息 | Krueppel-like factor 10 (KLF10) is a ~52 kDa protein. Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation. |
| 备注 | For research use only |
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