| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | EC:2.7.11.1, KIAA0551, TNIK, TRAF2 and NCK-interacting protein kinase |
| 免疫原 | E. coli - derived recombinant Human TNIK (Met1-Asp291). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UKE5 |
| 背景信息 | TRAF2 and NCK-interacting protein kinase (TNIK) is a ~154 kDa protein. Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. 1. Meng, Z. et al. (2015) Nature communications 6, 8357. PMID: 26437443 |
| 备注 | For research use only |