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Anti-Human TNIK Polyclonal Antibody|抗人TNIK多克隆抗体(靶标:人TRAF2和NCK相互作用激酶)

  • 货号:RB9THA247024
  • 价格:面议
  • 点击:499
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse
靶标EC:2.7.11.1, KIAA0551, TNIK, TRAF2 and NCK-interacting protein kinase
免疫原E. coli - derived recombinant Human TNIK (Met1-Asp291).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9UKE5
背景信息

TRAF2 and NCK-interacting protein kinase (TNIK) is a ~154 kDa protein. Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress.

1. Meng, Z. et al. (2015) Nature communications 6, 8357. PMID: 26437443
备注For research use only
【仅供科学研究使用】

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