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Anti-Human RAB26 Polyclonal Antibody|抗人RAB26多克隆抗体(靶标:人Ras相关蛋白Rab26)

  • 货号:RB9THD629014
  • 价格:面议
  • 点击:300

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human, Rat
靶标EC:3.6.5.2, RAB26, Ras-related protein Rab-26
免疫原E. coli - derived recombinant Human RAB26 (Asp61-Pro256).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9ULW5
背景信息

Ras-related protein Rab-26 (RAB26) is a ~27 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB26 mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland.

1. Li, C. et al. (2012) The Journal of biological chemistry 287, 42784-94. PMID: 23105096
2. Tian, X. et al. (2010) Molecular and cellular biology 30, 1269-84. PMID: 20038531
备注For research use only
【仅供科学研究使用】

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