| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human, Rat |
| 靶标 | EC:3.6.5.2, RAB26, Ras-related protein Rab-26 |
| 免疫原 | E. coli - derived recombinant Human RAB26 (Asp61-Pro256). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9ULW5 |
| 背景信息 | Ras-related protein Rab-26 (RAB26) is a ~27 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB26 mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. 1. Li, C. et al. (2012) The Journal of biological chemistry 287, 42784-94. PMID: 23105096 2. Tian, X. et al. (2010) Molecular and cellular biology 30, 1269-84. PMID: 20038531 |
| 备注 | For research use only |