Anti-Human HSP90AB1 Polyclonal Antibody|抗人HSP90AB1多克隆抗体(靶标：人热休克蛋白90β)
- 货号：RB9THY418014
- 价格：面议
- 点击：560
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human, Rat, Horse |
| 靶标 | HSP 84, HSP 90, HSP84, HSP90AB1, HSP90B, HSPC2, HSPC3, HSPCB, Heat shock 84 kDa, Heat shock protein HSP 90-beta, Heat shock protein family C member 3 |
| 免疫原 | E. coli - derived recombinant Human HSP90AB1 (Met1-Asp724). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重构方法 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输条件 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 产品使用说明 | ELISA: 1:2000-1:20000; WB: 1:500-1:2000 |
| 登录号 | P08238 |
| 背景信息 | Heat shock protein HSP 90-beta (HSP90AB1) is a ~83 kDa protein. Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. 1. Chadli, A. et al. (2006) Molecular and cellular biology 26, 1722-30. PMID: 16478993 2. Retzlaff, M. et al. (2009) EMBO reports 10, 1147-53. PMID: 19696785 3. Pearl, LH. (2016) Biopolymers 105, 594-607. PMID: 26991466 4. Verma, S. et al. (2016) Biochimie 127, 227-40. PMID: 27295069 5. Khurana, N. et al. (2015) Frontiers in oncology 5, 100. PMID: 25973397 6. Shang, Y. et al. (2014) Biochemical and biophysical research communications 446, 387-92. PMID: 24613385 7. Didelot, C. et al. (2008) Cell death and differentiation 15, 859-66. PMID: 18239673 8. Cheng, MB. et al. (2010) Cellular signalling 22, 1206-13. PMID: 20353823 9. Zhang, M. et al. (2020) Cell 181, 637-652.e15. PMID: 32272059 |
| 备注 | For research use only |
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