当前位置：首页>产品中心>单抗/多抗>Anti-Human CD303/CLEC4C Polyclonal Antibody|抗人CD303/CLEC4C多克隆抗体(靶标：人C型凝集素结构域家族4成员C/CD303)
Anti-Human CD303/CLEC4C Polyclonal Antibody|抗人CD303/CLEC4C多克隆抗体(靶标：人C型凝集素结构域家族4成员C/CD303)
- 货号：RB9THV560014
- 价格：面议
- 点击：531
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | BDCA-2, BDCA2, Blood dendritic cell antigen 2, C-type lectin domain family 4 member C, C-type lectin superfamily member 7, CD303, CLEC4C, CLECSF11, CLECSF7, DLEC, Dendritic lectin, HECL |
| 免疫原 | E. coli - derived recombinant Human CD303/CLEC4C (Ser67-Ile213). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8WTT0 |
| 背景信息 | C-type lectin domain family 4 member C (CD303/CLEC4C) is a ~25 kDa protein. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. 1. Dzionek, A. et al. (2001) The Journal of experimental medicine 194, 1823-34. PMID: 11748283 2. Riboldi, E. et al. (2011) The Journal of biological chemistry 286, 35329-35333. PMID: 21880719 3. Jégouzo, SA. et al. (2015) The Journal of biological chemistry 290, 16759-71. PMID: 25995448 |
| 备注 | For research use only |
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