| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | C2, C3/C5 convertase, Complement C2, Complement C2a, EC:3.4.21.43, Serine protease complement C2b |
| 免疫原 | E. coli - derived recombinant Human C2 (Ile245-His451). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P06681 |
| 背景信息 | Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507 3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
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| CRP单克隆抗体 | 8416 |
| 猫胰脂肪酶单克隆抗体 | 7560 |
| 马SAA单克隆抗体 | 8305 |
| 犬腺病毒单克隆抗体 | 7293 |
| 犬轮状病毒单克隆抗体 | 7377 |
| 犬血红蛋白单克隆抗体 | 8518 |
| 犬胰脂肪酶单克隆抗体 | 7168 |
| 犬松弛素单克隆抗体 | 7596 |
| 犬冠状病毒单克隆抗体 | 7568 |
| 犬瘟病毒单克隆抗体 | 7306 |
| 犬细小病毒单克隆抗体 | 7819 |
| 猫瘟病毒单克隆抗体 | 7983 |
| 猫疱疹病毒单克隆抗体 | 7678 |
| 猫杯状病毒单克隆抗体 | 8174 |
| 猫SAA单克隆抗体 | 7667 |
| 犬CRP单克隆抗体 | 8207 |
| 犬、猫IgG单克隆抗体 | 7518 |