| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CD265, ODFR, Osteoclast differentiation factor receptor, RANK, Receptor activator of NF-KB, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A |
| 免疫原 | E. coli - derived recombinant Human CD265/TNFRSF11A (Ser36-Ser195). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9Y6Q6 |
| 背景信息 | Tumor necrosis factor receptor superfamily member 11A (CD265/TNFRSF11A) is a ~66 kDa protein. Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells. 1. Nakagawa, N. et al. (1998) Biochemical and biophysical research communications 253, 395-400. PMID: 9878548 |
| 备注 | For research use only |