当前位置:首页>产品中心>单抗/多抗>Anti-Human CD265/TNFRSF11A Polyclonal Antibody|抗人CD265/TNFRSF11A多克隆抗体(靶标:人肿瘤坏死因子受体超家族成员11A/RANK/CD265)

Anti-Human CD265/TNFRSF11A Polyclonal Antibody|抗人CD265/TNFRSF11A多克隆抗体(靶标:人肿瘤坏死因子受体超家族成员11A/RANK/CD265)

  • 货号:RB9THV008014
  • 价格:面议
  • 点击:226
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标CD265, ODFR, Osteoclast differentiation factor receptor, RANK, Receptor activator of NF-KB, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A
免疫原E. coli - derived recombinant Human CD265/TNFRSF11A (Ser36-Ser195).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9Y6Q6
背景信息

Tumor necrosis factor receptor superfamily member 11A (CD265/TNFRSF11A) is a ~66 kDa protein. Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.

1. Nakagawa, N. et al. (1998) Biochemical and biophysical research communications 253, 395-400. PMID: 9878548
备注For research use only
【仅供科学研究使用】

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