| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | ETBR-LP-2, ETBRLP2, Endothelin B receptor-like protein 2, G-protein coupled receptor 37-like 1, GPR37L1 |
| 免疫原 | E. coli - derived recombinant Human GPR37L1 (Ala26-Met134). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O60883 |
| 背景信息 | G-protein coupled receptor 37-like 1 (GPR37L1) is a ~52 kDa protein. G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. 1. Coleman, JL. et al. (2016) Science signaling 9, ra36. PMID: 27072655 2. Meyer, RC. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 9529-34. PMID: 23690594 3. Giddens, MM. et al. (2017) Neurobiology of disease 106, 181-190. PMID: 28688853 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 黄曲霉毒素B1抗原抗体 | 5862 |
| 黄曲霉毒素M1抗原抗体 | 5909 |
| 黄曲霉毒素总量抗原抗体 | 6115 |
| 赭曲霉毒素抗原抗体 | 5694 |
| 玉米赤霉烯酮/ 玉米赤霉醇抗原抗体 | 5943 |
| 伏马毒素B1(烟曲霉)抗原抗体 | 5488 |
| T-2毒素抗原抗体 | 5540 |
| 呕吐毒素抗原抗体 | 5310 |
| 桔霉素抗原抗体 | 6123 |
| 杂色曲霉素抗原抗体 | 5830 |
| 交联孢酚抗原抗体 | 5605 |
| 蓖麻毒素抗原抗体 | 5824 |
| 微囊藻毒素LR抗原抗体 | 5671 |
| 微囊藻毒素RR抗原抗体 | 5397 |
| 微囊藻毒素YR抗原抗体 | 5970 |
| 白喉毒素抗原抗体 | 5413 |
| 霍乱毒素抗原抗体 | 5556 |
| 肉毒杆菌毒素A/B/D/E抗原抗体 | 5925 |
| 大肠杆菌肠毒素抗原抗体 | 6185 |
| 棒曲霉素/展青霉素抗原抗体 | 5625 |