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Anti-HHV-5/HCMV UL83 Polyclonal Antibody|抗HHV-5/HCMV UL83多克隆抗体(靶标：人巨细胞病毒磷蛋白pp65/UL83)

形态	Liquid
宿主种属	Rabbit
克隆性	Polyclonal
抗体亚型	IgG
纯化方式	Purified by antigen affinity column.
内毒素水平	Please contact with the lab for this information.
应用	ELISA, IHC, WB
种属反应性	Human cytomegalovirus
靶标	65 kDa matrix phosphoprotein, 65 kDa phosphoprotein, Phosphoprotein UL83, Tegument protein UL83, UL83, pp65
免疫原	E. coli - derived recombinant HHV-5/HCMV UL83 (Thr297-Tyr510).
储存缓冲液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号	P06725
背景信息	65 kDa phosphoprotein (UL83) is a ~62 kDa protein. Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus. Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1. Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes. 1. Abate, DA. et al. (2004) Journal of virology 78, 10995-1006. PMID: 15452220 2. Biolatti, M. et al. (2018) Journal of virology 92. PMID: 29263269 3. Cox, JB. et al. (2025) Journal of virology 99, e0048125. PMID: 40243337 4. Cristea, IM. et al. (2010) Journal of virology 84, 7803-14. PMID: 20504932
备注	For research use only

【仅供科学研究使用】

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