当前位置:首页>产品中心>单抗/多抗>Anti-Influenza A virus PA/Polymerase Acidic Protein Polyclonal Antibody|抗甲型流感病毒PA/聚合酶酸性蛋白多克隆抗体(靶标:甲型流感病毒聚合酶酸性蛋白)

Anti-Influenza A virus PA/Polymerase Acidic Protein Polyclonal Antibody|抗甲型流感病毒PA/聚合酶酸性蛋白多克隆抗体(靶标:甲型流感病毒聚合酶酸性蛋白)

  • 货号:RB9TVK560014
  • 价格:面议
  • 点击:529
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Influenza A virus
靶标EC:3.1.-.-, PA, Polymerase acidic protein, RNA-directed RNA polymerase subunit P2
免疫原E. coli - derived recombinant Influenza A virus PA/Polymerase Acidic Protein (Glu2-Gly209).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P03433
背景信息

Polymerase acidic protein (PA) is a ~82 kDa protein. Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.

备注For research use only
【仅供科学研究使用】

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